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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '423e7ef3f2fe2af7d896d146ee5def832a0782d309d1678852b6e73bb77f280a' 
  AND token = 'SpF9u4lqqH+Gwt7Lk/1NVF5R+Tu/ODaAFieV08wp48E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}