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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '883e6cdcbacba55ca4916f15e950cfb74601b4fda0ac18be353738951633fe0b' 
  AND token = 'AdTwo9JlcT3rYR9U8Yt/e0FlRgCxpf6HtC9kvtFdHws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}