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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1182a27b289006864bb543ada79a2ddc2244ee3d47cec0bcb3d4320b88d69e19' 
  AND token = 'VdOY+shbpGlGOkX+/4Y6O/l1oJJt5Z8jyZ06xDPcuiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}