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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4116b6ff57b091c75c814b9c3fbe88e97c86a69e900340f0d260e02c7dc566e2' 
  AND token = '2+7n9epQcTs74XFut+kLwj1tl59C/4Whz4tgTIQFdGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}