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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa44008d81c7de89c78ad0050b14b378c1f08c7de1447f5bbee3c3a878c1c9a0' 
  AND token = 'wv8Vf/3bmHU6cpZbpiz6/Qa9t47eUuVmqCKAF9ZOUnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}