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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f03fc58ab4b08d86c23f7fb3c05c03554e8899973b6bda49b05dd100c02d7a01' 
  AND token = '66UqWuoRJw7X7cehYRSEH5dC61hIPCemrGefSUdtrGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}