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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17c1d797fd6f0c25cee81c381d77bdab77e5a0d611466bef79f6730dc1e29433' 
  AND token = 'vBXHyvXXbUfoYb0bUvuqSwxnNxcIZCi2OBDZdyV2WqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}