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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '080bf63646ee16c7bae6369aabc84321b64a1aee421340716c94d439b8a7a756' 
  AND token = 'cpMj1OK2K6Dv2TRlHIJPvj6Rt/a1lbh3SgKAqa2drj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}