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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800d0a1f4a2e6e71a5845dc06a790425670320fda4ce26f96061fe0de9ef82f8' 
  AND token = 'weYlUwRBTVobqhLxOCsRzndMgppOo38PyhslXjEa2K0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}