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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5021556c9f719990224d855ccf557e53cc0a9f0585fcc8a1f63a1b7a196fc8bd' 
  AND token = 'UxCP4pTy/3RJrio6n3CxBKW3zLGDqqN3eMcQFhyqnJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}