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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2586fda684ba92253779994aca2c20abe1f03fd441070ab41f0f642102b11858' 
  AND token = 'WdWeHHWVYAyn6whhU3K9Tx7Mwb/Y459XE6eUYfSols0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}