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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14161230eb4415939d39f2a01ac5813dce891a4dc0c694a87d80e85494ebfd66' 
  AND token = 'CVpBY4Tgm7cspz6pej5SE1FJgNltwhgnRppaJ4fshJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}