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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5bf371fc6a8b30b31856786bfc951c71e3e7e8eed8f026f3e35c8eb188d913' 
  AND token = 'IJzQrfba1e+SuC2FDRBvO8lXW7g44CGjuSFUxGaHyGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}