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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f5cdf5bfb2a8abfa415b3ec45c7df018e50e76a28f64ae9a1b0894680ad417f' 
  AND token = 'JipFE9pGl2exGQjegZOyG8lOjpcewnW67B6Bope61ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}