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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fcc25602bb6e0d70f4a860f30d1c1f9145e7fe1349e21e1fbb456ace75d8610' 
  AND token = 'BkWstx0uwaHFQfvi2g8TpGL854qg69/4ADMAnOf2Zu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}