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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cf9e1a828b75c41174371b7f3a7b36fa3cfaa946be1667b4f59786a30b1bae2' 
  AND token = 'Z1LVNIbgyJZ8565F14pUP7c8uXo+ik8W+wYUSA/sTj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}