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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f0cb5dd2420c428b27624a76fe13b5e7bd5f715316a8f165c6fd9049378d474' 
  AND token = 'HqEi+1FB1p4H4Lj7f8Mw0eyNKZh8BjG45MAoSEbIWiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}