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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0106a5647d9221dff1e6d07f6814d2d03c7b6390755f42ff31208395e58b208f' 
  AND token = 'kDZMe+au0jWumHDGYuUHn4Tyb4tgMvFGH08tO6c9aRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}