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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1159aa56794400dd6fee3a632c46a96dc61bab6d36ade1ffd8331e420eedaa9' 
  AND token = 'Qk7GLb3AVhab643WMkyVDXX9/JHROqlmV0Jtk+MFhko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}