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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c01d3c9d127b5d0a3b938d7909a419deb3891afb4fa60f532d68640b4af4405' 
  AND token = 'drDXhZ1wRlCjec71jVT/Slh/aO8a111a46DnmRNocA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}