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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14957649f7f32b865f7fec9a4e779fee337ecc5ed69f9e2762f4029e9f049418' 
  AND token = 'n0rq+VN2UdktKQo2nWkNqqCR6H+hJZ744LN5ORRSqLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}