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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a74b122a9586fa8eb8de5cdf221eddf6d473af5aac91c16748233810163fc2' 
  AND token = 'clKnlq8Wy+LEL5MmREdZPeeRL+UsfCQyJT0XzEj0csg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}