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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03c6e1d02015327dd605d0e3a18b00cec2cd51f51d03f369debb6ab44fd7cbf2' 
  AND token = 'rNR1NE+pibB1rHLh0ZrUw71Lu8C+8cfiUfBrbFAM/W4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}