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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '278346c3ef060d3db1bd850b6dc02a5dc7772676cf6c1c6c8466eed8d6c54baf' 
  AND token = 'wjE78P9j7jPsyKxYfJ96jmyrtqB+WN4mFjp9oUH1QVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}