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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f0f65b563f12f6169d71092cc8b22283c2ff260845cc25c39c8145d4fe55d18' 
  AND token = 'a/XmREcQPR0Q8T6w+0kBFxfj2ABz3wY3JBiBtR89r9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}