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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c385a1d3371c687799997330154dba3189a8e4aee563d7598808a53542874f82' 
  AND token = '4/lJUjwTDjUJUyzI8W+UqbegC/Mt8QrlLRZG16iUIvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}