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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c3f71d7e74fc8eae02b6c2680d36fe4253f48906be70c0f354665a34d80035d' 
  AND token = '5SxI5Fdf/EBvC7NTaBFzN3X/10kNkcOIkjSsnVvMeVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}