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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '203706b4df34928e8f5c1f39315907c478f1f01aa191ca044037db54921f3578' 
  AND token = 'I/v6GoiN57UtWD3o0v1gLtupFcUxQAS8NYCA0JGjY5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}