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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d853284b4c65b94b74ad38607b71dc57301ee354c31587e78e451d471e330eb' 
  AND token = 'WMElV1g1ZwpzAg70bCVxAdpbMKUoX1Drm3XUU0lwwdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}