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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '899b12e0aeb2df7eb77b75288020307b7089bda095ccd7ae719400ac9b3a0a0f' 
  AND token = 'Qn2J1zuhFpZv4YZ/9/ZVosM3ZomW6SNBOW77ye3pMA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}