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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edcd6ed165ae17e09cafcaf68a3a20c32b8af7df44300b40f24c46e9df370bb8' 
  AND token = 'BHJ40KfpOHNaOUaFxQRSoaAKUfAEA5YaNnOuqO5znc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}