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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e87d45274d1310d470604c6a8f383ef2a5bc6aa28e0b6269d52e336802e1d2e' 
  AND token = 'unLKpFTg5zvmXEtDoKsei7FnLK6eO6CRsczDN9fAwZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}