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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e0097fca44153051cb7cdfe8f38dfa40558833ba4f455c51d081c8b4de3c30e' 
  AND token = 'OyW2CnB6gNAT7pSx++fubNxLATi1LHoI9CKWKi/2/tQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}