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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cd2ee21855e51b1a278eaef0f9b2ded52859217fa32ed484ce1d0159f2b80ed' 
  AND token = 'NSJXo4tTdJaXDAyd/+JJVVTRIDBXkEQjXh8ODiPIqlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}