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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16c304e8bb23fe758664c9d5b702600af1ea15f5ae9ae726ac3f1b0f070d46e9' 
  AND token = 'E/NiepE73Xy42+2+x3UbXS7lA6kjpRHqq9aviKMMl+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}