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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6db47ab162fbbb36d84e321b1a0d1d154591fd9b6dbbc3a8403c40a4a95182f' 
  AND token = 'dZidNOGVaFpM5+bmOzd1bPXPMzzT7RaYm+njjI2xZxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}