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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57fb68792a7e8f67289ff1c43c0c1d722ee95607c2c80ebb3e158cebaeb01959' 
  AND token = 'rpyUlXbPvYkx7IWv3gWmdqSlLf0lm6KMgXAj8Y2I9dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}