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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc6821b00ac079157a6dfcfb77ce37168b2a779a4bac1d8b219cd07e794f78ce' 
  AND token = 'KsoxiVthM7zbSOdMrw7NA6a1uyikYck3P5bRExhX7f4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}