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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15a026ecfeb1a792530e7cc9c19a5fa657dc2a943da2d78fa5b5b60a32163149' 
  AND token = 'IIUGdv3WTmtUsvCp4EklceSAX6Y41O4csF5Fi60J5AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}