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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b6fa704212b3bbd72a9093f5ce2e57b846b3ea0e523b043ccff08e9c4c3daa4' 
  AND token = 'DVwbhAHXqpl7DlufGl7uIa6DK/unj7hH7y56ayf3onQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}