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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '647f506b5330f9093c889e62e25c434f31e0c98ea1856c392bd7a36b620458c1' 
  AND token = 'vmEiyWYTSttekoq0eLJ5OtjojX6qLNekN58n7o/PReA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}