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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e061cfe1d3f10577fe0838bd1da85151a35756ecb01b3460cbdd68fe78b8ab' 
  AND token = 'tF8pLzaKF7tefJxIsy73jY0LrYPXCYvYpr5rrj5Arfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}