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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b544a314cb273db209fdf9162ea5ff2b39aa603cc1b3dd2fa916f4d16004e88c' 
  AND token = 'fiCST+I57UfVYQqGlc0RB2sHmKadcyb61rNWcJdichM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}