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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eac288dbf5649d4e43dd6d4a65a4d2784671c2b51424c3e592c55029ca358a6e' 
  AND token = 'lC5XY2pJWcrFdYdmO/DkSNRg+uIbQ2ngNVaJkdqs+z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}