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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0227f4ac2720243fcb0c8f08fc29bbcdb422897e7c1d74f92623ab3badfd2ff1' 
  AND token = 'dixRQSeeYp/T0jRH/4I1ZTlTBWO7ZogDs0iBR9FD0Ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}