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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d614194b452d49aeff3a7c5c5a016893c6ae2483e3a1a0d741b296bbaa7b90d' 
  AND token = 'VUeBmBuDpjK2Pod0rx3RPfbW3sdRDEpk7GjQcRS5uBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}