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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0412defcd22ee8f71f4dea70bf31dae522f072a0ffb54542fb042f9b919f1faa' 
  AND token = 'aqFnr4ZQMHAHzWxXjBrgxSMaFWhLlG0hdD5PIQ9eIX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}