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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e23e884a0386d786657cd929f92c418f4ab3cb54a163c49e98e383f218176d9a' 
  AND token = 'iitR0cZLVWXM5x+sasA3fW920LWE83tngu/gPUcHFYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}