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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '535ae9f84f032291feb39ce7533d7027c3c50cf38c8c1284bbb08c27b2d158a6' 
  AND token = '5JwW0OUOBe2sbjlGgNAp0t2fcNsGMEBWuDY9/9I4IA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}