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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a19b64d21d430ccfa6822c4074ea8c4a68fca0c8d97a61420019595836fcdc36' 
  AND token = 'zxEQjidNI2u2gsPqEqIP1D/Y0Fs3gThGuxMP0RhzxPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}